The Clarke Historical Museum (formerly the Clarke Memorial Museum) in Downtown Eureka contains the area's premier collection of far California's North Coast regional and cultural history, with significant focus on the 19th Century Victorian era. The facility has an entire Native American wing, which features an extensive internationally recognized collection of basketry, regalia, stoneware, implements, and other objects indicative of the culture and creativity of local and regional Native American group

The museum is housed in the former Bank of Eureka & Savings Bank of Humboldt Building (1911) in Old Town Eureka, which is listed on the National Register of Historic Places. The bank building is a Classical Revival of Neoclassical structure, notable for its elevations, which are covered in glazed architectural terra-cotta over brick. It is the most significant structure covered in this material north of San Francisco. Quoined pavilions flank the recessed portico supported by iconic columns and an extensive balustraded parapet appears above the cornice.